The hilarity begins when professor Sherman Klump finds romance with fellow DNA specialist, Denise Gaines, and discovers a brilliant formula that reverses aging. But Sherman's thin and obnoxious alter ego, Buddy Love, wants out...and a big piece of the action. And when Buddy gets loose, things get seriously nutty.
Sherman Klump / Buddy Love / Granny Klump / Mama Klump / Papa Klump / Young Papa Klump / Ernie Klump / Lance Perkins
Denise
Dean Richmond
Jason
Denise's Father
Denise's Mother
Leanne Guilford
Ernie Klump, Jr.
Issac
Restaurant Manager
Restaurant Trainee
Dr. Knoll
Bright Student
Claudine
Old Willie
Chantal
Stripper
Preacher
Bridesmaid
Bridesmaid
Party Guest / Bridesmaid
Party Guest
Mrs. Dudikoff
Receptionist
Man in Bathroom
Man in Bathroom
Zeke
Baby Buddy
Baby Buddy
Baby Buddy
Boardroom Member
Boardroom Member
Guy in Elevator
Dancer
Dancer
Dancer
Dancer
Buddy at 15
Sweet Old Lady with Dog
Buxom Student
Fraternity Student
Lecture Student
Heavyset Woman
Krusty Reporter
Cab Driver
Four Star General
Scientist
Scientist
Newscaster
Scared Popcorn Man
Scared Popcorn Man
Scared Hot Dog Vendor
Scared Little Girl
Denise's Nosy Neighbor (uncredited)
Editor
Executive Producer
Executive Producer
Director
Executive Producer
Director of Photography
Producer
Executive Producer
Screenplay
Screenplay
Executive Producer
Screenplay
Screenplay
Music Coordinator
Makeup Designer
Original Music Composer
Story
Characters
Story
Story
Associate Producer
Music Supervisor
Visual Effects Supervisor
Music Supervisor
Special Effects Makeup Artist
Co-Producer
Costume Design
Camera Operator
Co-Producer
Production Design
Stunt Coordinator
Boom Operator
Stunt Coordinator
Cableman
Script Supervisor
Unit Publicist
Still Photographer
Sound Mixer
Art Direction
Set Decoration
Makeup Department Head
Writer
Title Designer